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Event based Light

Neural Information Processing Systems

Event-based structured light (SL) systems have attracted increasing attention for their potential in high-performance 3D measurement. Despite the inherent HDR capability of event cameras, reflective and absorptive surfaces still cause event clutter and absence, which produce overexposed and underexposed regions that degrade the reconstruction quality. In this work, we present the first HDR 3D measurement framework specifically designed for event-based SL systems. First, we introduce a multi-contrast HDR coding strategy that facilitates imaging of areas with different reflectance. Second, to alleviate inter-frame interference caused by overexposed and underexposed areas, we propose a universal confidence-driven stereo matching strategy. Specifically, we estimate a confidence map as the fusion weight for features via an energy-guided confidence estimation.


Common Task Framework For a Critical Evaluation of Scientific Machine Learning Algorithms

Neural Information Processing Systems

Machine learning (ML) is transforming modeling and control in the physical, engineering, and biological sciences. However, rapid development has outpaced the creation of standardized, objective benchmarks--leading to weak baselines, reporting bias, and inconsistent evaluations across methods. This undermines reproducibility, misguides resource allocation, and obscures scientific progress. To address this, we develop a Common Task Framework (CTF) for scientific machine learning. The CTF features a curated set of datasets and task-specific metrics spanning forecasting, state reconstruction, and generalization under realistic constraints, including noise and limited data. Inspired by the success of CTFs in fields like natural language processing and computer vision, our framework provides a structured, rigorous foundation for head-to-head evaluation of diverse algorithms.


Learning to Zoom with Anatomical Relations for Medical Structure Detection

Neural Information Processing Systems

Accurate anatomical structure detection is a critical preliminary step for diagnosing diseases characterized by structural abnormalities. In clinical practice, medical experts frequently adjust the zoom level of medical images to obtain comprehensive views for diagnosis.


From Likelihood to Fitness: Improving Variant Effect Prediction in Protein and Genome Language Models

Neural Information Processing Systems

Generative models trained on natural sequences are increasingly used to predict the effects of genetic variation, enabling progress in therapeutic design, disease risk prediction, and synthetic biology. In the zero-shot setting, variant impact is estimated by comparing the likelihoods of sequences, under the assumption that likelihood serves as a proxy for fitness. However, this assumption often breaks down in practice: sequence likelihood reflects not only evolutionary fitness constraints, but also phylogenetic structure and sampling biases, especially as model capacity increases. We introduce Likelihood-Fitness Bridging (LFB), a simple and general strategy that improves variant effect prediction by averaging model scores across sequences subject to similar selective pressures. Assuming an Ornstein-Uhlenbeck model of evolution, LFB can be viewed as a way to marginalize the effects of genetic drift, although its benefits appear to extend more broadly. LFB applies to existing protein and genomic language models without requiring retraining, and incurs only modest computational overhead. Evaluated on largescale deep mutational scans and clinical benchmarks, LFB consistently improves predictive performance across model families and sizes. Notably, it reverses the performance plateau observed in larger protein language models, making the largest models the most accurate when combined with LFB. These results suggest that accounting for phylogenetic and sampling biases is essential to realizing the full potential of large sequence models in variant effect prediction.


Self supervised learning for in vivo localization of microelectrode arrays using raw local field potential

Neural Information Processing Systems

Recent advances in large-scale neural recordings have enabled accurate decoding of behavior and cognitive states, yet decoding anatomical regions remains underexplored, despite being crucial for consistent targeting in multiday recordings and effective deep brain stimulation. Current approaches typically rely on external anatomical information, from atlas-based planning to post hoc histology, which are limited in precision, longitudinal applicability, and real-time feedback. In this work, we develop a self-supervised learning framework, Lfp2vec, to infer anatomical regions directly from the neural signal in vivo. We adapt an audiopretrained transformer model by continuing self-supervised training on a large corpus of unlabeled local-field-potential (LFP) data, then fine-tuning for anatomical region decoding. Ablations show that combining out-of-domain initialization with in-domain self-supervision outperforms training from scratch. We demonstrate that our method achieves strong zero-shot generalization across different labs and probe geometries, and outperforms state-of-the-art self-supervised models on electrophysiology data. The learned embeddings form anatomically coherent clusters and transfer effectively to downstream tasks like disease classification with minimal fine-tuning. Altogether, our approach enables zero-shot prediction of brain regions in novel subjects, demonstrates that LFP signals encode rich anatomical information, and establishes self-supervised learning on raw LFP as a foundation to learn representations that can be tuned for diverse neural decoding tasks.


SDPGO: Efficient Self-Distillation Training Meets Proximal Gradient Optimization

Neural Information Processing Systems

Self-knowledge distillation (SKD) enables single-model training by distilling knowledge from the model's own output, eliminating the need for a separate teacher network required in conventional distillation methods. However, current SKD methods focus mainly on replicating common features in the student model, neglecting the extraction of key features that significantly enhance student learning. Inspired by this, we devise a self-knowledge distillation framework entitled Self-Distillation training via Proximal Gradient Optimization or SDPGO, which utilizes gradient information to identify and assign greater weight to features that significantly impact classification performance, enabling the network to learn the most relevant features during training. Specifically, the proposed framework refines the gradient information into a dynamically changing weighting factor to evaluate the distillation knowledge via the dynamic weight adjustment scheme. Meanwhile, we devise the sequential iterative learning module to dynamically optimize knowledge transfer by leveraging historical predictions and real-time gradients, stabilizing training through mini-batch-based KL divergence refinement while adaptively prioritizing task-critical features for efficient self-distillation. Comprehensive experiments on image classification, object detection, and semantic segmentation demonstrate that our method consistently surpasses recent state-of-the-art knowledge distillation techniques.


Disentangling Misreporting from Genuine Adaptation in Strategic Settings: ACausal Approach

Neural Information Processing Systems

In settings where ML models are used to inform the allocation of resources, agents affected by the allocation decisions might have an incentive to strategically change their features to secure better outcomes. While prior work has studied strategic responses broadly, disentangling misreporting from genuine adaptation remains a fundamental challenge. In this paper, we propose a causally-motivated approach to identify and quantify how much an agent misreports on average by distinguishing deceptive changes in their features from genuine adaptation. Our key insight is that, unlike genuine adaptation, misreported features do not causally affect downstream variables (i.e., causal descendants). We exploit this asymmetry by comparing the causal effect of misreported features on their causal descendants as derived from manipulated datasets against those from unmanipulated datasets. We formally prove identifiability of the misreporting rate and characterize the variance of our estimator. We empirically validate our theoretical results using a semi-synthetic and real Medicare dataset with misreported data, demonstrating that our approach can be employed to identify misreporting in real-world scenarios.


DermaCon-IN: AMulti-concept Annotated Dermatological Image Dataset of Indian Skin Disorders for Clinical AIResearch

Neural Information Processing Systems

Artificial intelligence is poised to augment dermatological care by enabling scalable image-based diagnostics. Yet, the development of robust and equitable models remains hindered by datasets that fail to capture the clinical and demographic complexity of real-world practice. This complexity stems from region-specific disease distributions, wide variation in skin tones, and the underrepresentation of outpatient scenarios from non-Western populations. We introduce DermaCon-IN, a prospectively curated dermatology dataset comprising 5,450 clinical images from 3,002 patients across outpatient clinics in South India. Each image is annotated by board-certified dermatologists with 245 distinct diagnoses, structured under a hierarchical, aetiology-based taxonomy adapted from Rook's classification. The dataset captures a wide spectrum of dermatologic conditions and tonal variation commonly seen in Indian outpatient care. We benchmark a range of architectures, including convolutional models (ResNet, DenseNet, EfficientNet), transformerbased models (ViT, MaxViT, Swin), and Concept Bottleneck Models to establish baseline performance and explore how anatomical and concept-level cues may be integrated. These results are intended to guide future efforts toward interpretable and clinically realistic models. DermaCon-IN provides a scalable and representative foundation for advancing dermatology AI in real-world settings.


Semi-supervised Vertex Hunting, with Applications in Network and Text Analysis

Neural Information Processing Systems

Vertex hunting (VH) is the task of estimating a simplex from noisy data points and has many applications in areas such as network and text analysis. We introduce a new variant, semi-supervised vertex hunting (SSVH), in which partial information is available in the form of barycentric coordinates for some data points, known only up to an unknown transformation. To address this problem, we develop a method that leverages properties of orthogonal projection matrices, drawing on novel insights from linear algebra. We establish theoretical error bounds for our method and demonstrate that it achieves a faster convergence rate than existing unsupervised VH algorithms. Finally, we apply SSVH to two practical settings-- semi-supervised network mixed membership estimation and semi-supervised topic modeling--resulting in efficient and scalable algorithms.


Machine Unlearning under Overparameterization

Neural Information Processing Systems

Machine unlearning algorithms aim to remove the influence of specific training samples, ideally recovering the model that would have resulted from training on the remaining data alone. We study unlearning in the overparameterized setting, where many models interpolate the data, and defining the solution as any loss minimizer over the retained set--as in prior work in the underparameterized setting--is inadequate, since the original model may already interpolate the retained data and satisfy this condition. In this regime, loss gradients vanish, rendering prior methods based on gradient perturbations ineffective, motivating both new unlearning definitions and algorithms. For this setting, we define the unlearning solution as the minimum-complexity interpolator over the retained data and propose a new algorithmic framework that only requires access to model gradients on the retained set at the original solution. We minimize a regularized objective over perturbations constrained to be orthogonal to these model gradients, a first-order relaxation of the interpolation condition. For different model classes, we provide exact and approximate unlearning guarantees and demonstrate that an implementation of our framework outperforms existing baselines across various unlearning experiments.